MadWorldDetox

Protocol Overview

1. Get out of exposure — You cannot detox while still being exposed
2. Bind mycotoxins — Charcoal, cholestyramine, clay, welchol
3. Support detox pathways — Glutathione, sweating, drainage
4. Address colonization — Sinuses, gut (if present)
5. Rebuild — Mitochondria, hormones, immune system

Step 0: Get Out of Exposure

Non-Negotiable

You cannot detox from mold while continuing to be exposed. No supplement protocol will work if you're still living or working in a moldy environment. This is the step most people skip — and why most people fail to recover.

→Test your home (ERMI, HERTSMI-2, or professional inspection)
→If mold is present: remediate professionally OR move
→Don't bring contaminated belongings to new space
→Consider workplace, car, other environments

Testing for Mold Illness

Environment Testing

• ERMI: Environmental Relative Moldiness Index. DNA-based, comprehensive.
• HERTSMI-2: Focuses on the 5 most toxic mold species.
• Professional inspection: Visual + moisture detection + air sampling.

Personal Testing

• Mycotoxin urine test: Great Plains, RealTime Labs, Vibrant Wellness. Shows which mycotoxins you're excreting.
• HLA-DR genetic testing: ~25% of people have genes that make them mold-susceptible.
• C4a, TGF-beta1, MMP-9: Inflammatory markers in Shoemaker protocol.
• VCS (Visual Contrast Sensitivity): Free online screening test.

Phase 1: Binders (Core Protocol)

Mycotoxins recirculate through enterohepatic circulation. Binders catch them in the gut and escort them out. This is the foundation of mold detox.

MOST EFFECTIVE (Rx)

Cholestyramine (CSM)

Prescription bile acid sequestrant. Gold standard in Shoemaker protocol. Extremely effective for ochratoxin, gliotoxin.

• Dose: 4g 4x daily (work up gradually)
• Take 30+ min before meals and other supplements
• Can cause constipation — manage with magnesium
• Requires prescription

Welchol (Colesevelam)

Prescription alternative to CSM. Better tolerated by some. May be less effective for certain mycotoxins.

• Dose: 625mg tablets, 3-6 daily
• Easier to take than CSM powder
• Less constipating

Activated Charcoal (OTC)

Broad-spectrum binder. Good for multiple mycotoxin types. Available without prescription.

• Dose: 1-2g 2-3x daily
• Take 2+ hours from food/supplements/meds
• Can cause constipation

Bentonite Clay (OTC)

Good for aflatoxin, zearalenone. Gentler than charcoal. FDA-approved for aflatoxin in animal feed.

• Dose: 1/2-1 tsp in water 1-2x daily
• Food-grade only
• Away from medications

Zeolite (OTC)

Binds mycotoxins plus heavy metals. Good addition to protocol.

• Dose: 1g 2x daily
• Between meals

Rotation: Some practitioners rotate binders (different ones bind different mycotoxins). Others stack multiple simultaneously.

Phase 2: Detox Support

Glutathione

Mycotoxins deplete glutathione. Replenishing supports Phase II detox.

• Liposomal glutathione 500mg daily
• Or NAC 600-1200mg daily (precursor)
• Caution: can mobilize too fast — start low

Sweating

Mycotoxins excrete in sweat. Sauna is powerful support.

• Infrared sauna 3-5x/week
• Shower immediately after
• Take binder before

Drainage

Bowels must move. Liver and lymph must flow.

• 2-3 bowel movements daily (add magnesium if needed)
• Castor oil packs over liver
• Lymphatic movement (rebounding, dry brushing)

Ozone

Ozone therapy (IV, insufflation, or water) can help with mycotoxin breakdown and infection.

Phase 3: Address Colonization

Some mold-ill patients have actual fungal colonization in sinuses or gut. This must be treated or you'll never fully recover.

Sinus Colonization

• MARCoNS (Multiple Antibiotic Resistant Coagulase Negative Staph) often present
• BEG spray (Bactroban/EDTA/Gentamicin) — prescription nasal spray
• Argentyn 23 (colloidal silver) nasal spray
• Xylitol nasal rinse

Gut Colonization

• Test: GI Map or similar comprehensive stool test
• Antifungal herbs: oregano oil, berberine, caprylic acid
• Prescription: Nystatin, fluconazole if severe
• Low-mold diet during treatment

Phase 4: Rebuilding

Once mycotoxins are clearing and colonization is addressed, rebuild what was damaged:

→Mitochondria: CoQ10, PQQ, NAD+ precursors. Mold damages mitochondria severely.
→Hormones: Check thyroid, adrenals, sex hormones. Mold disrupts all of them.
→Immune system: May need immune-modulating support. Work with practitioner.
→Nervous system: DNRS, Gupta program, or similar limbic system retraining can help reset stuck fight-or-flight response.
→Gut: Repair intestinal lining, restore microbiome diversity.

Timeline

Months 1-3: Remove from exposure. Start binders. May feel worse initially (Herx reactions).

Months 3-6: Binder protocol in full swing. Symptoms stabilizing. Address colonization.

Months 6-12: Significant improvement. Rebuilding phase begins.

12-24+ months: Full recovery for most. Some with severe illness or HLA-susceptibility take longer.

This is not a quick fix. Mold illness can take years to fully resolve. But people do recover.

Mycotoxin Binders Ranked →Cholestyramine Alternatives Glutathione Guide

Mold Detox Protocol: The Complete Guide